| Sanomat | Need To Change | Audiofly Remix | 125 | — | Global Scum Records | 2007 |
| Santana Feat. Mana | Corazon Espinado (a Thorn In My Heart) | Spanish-english Dance Remix | 125 | — | Arista Records | 2000 |
| Santana Feat. Mana | Corazon Espinado (a Thorn In My Heart) | Spanish/english Dance Remix | 125 | — | Arista Records | 2000 |
| Santini & Tellez | Lost Thoughts | Original Mix | 125 | — | Thoughtless Music | 2012 |
| Sarah Jaffe | Mannequin Woman | — | 125 | Top 40 | Kirtland | 2013 |
| Sardar | Party Life | Jump Smokers Quick Edit | 125 | Dance | We Got The Juice | 2012 |
| Sardar | Party Life | Jump Smokers Intro Edit | 125 | Dance | We Got The Juice | 2012 |
| Sardar | Party Life | Jump Smokers Radio Edit | 125 | Dance | We Got The Juice | 2012 |
| Sasanya ft. South Black | Zum Zum | KC Anderson Future House Remix | 125 | House | KC Anderson Future House Remix | 2018 |
| Sasha | Ripcord | Original Mix | 125 | Tech House | Last Night On Earth | 2019 |
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| Sasha Lazard | Battle Of Erishkigal | Wes Wallace Full Vocal | 125 | — | Omtown/higher Octave Music | 2003 |
| Sati Kazanova | Happiness Hey | — | 125 | Top 40 | Ragoza | 2017 |
| Savage Garden | The Animal Song | Hex Hector's Club Mix | 125 | — | Columbia Records | 1999 |
| Savatage | Hall Of The Mountain King | — | 125 | Rock | Atlantic | 2013 |
| Scorpions | Rock You Like A Hurricane | — | 125 | — | Polygram | 2006 |
| Scott Hardkiss | Beat Freak | Album Version | 125 | — | God Within | 2009 |
| Scott Langley | I Wanna Go | Original Mix | 125 | — | CDR | 2010 |
| Scotty Boy | Downtown | Original Mix | 125 | House | Original Mix | 2018 |
| Scotty Boy & Lizzie Curious | You're Not Alone | Original Mix | 125 | House | 418 | 2017 |
| Scotty Boy & Lizzie Curious | You're Not Alone | Sted-E & Hybrid Heights Remix | 125 | House | 418 | 2017 |
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| Scotty Boy & Lizzie Curious | You're Not Alone | — | 125 | — | 418 | 2017 |
| Scritti Politti | All That We Are | — | 125 | — | — | — |
| Seal | Waiting For You | The Passengerz Edit | 125 | Dance | Warner Bros. | 2004 |
| Seal | Waiting For You | The Passengerz Remix Edit | 125 | — | Warner Bros Records | 2004 |
| Sean Finn & Corona | The Rhythm Of The Night | — | 125 | Dance | — | 2019 |