| El Poder Del Norte | Ya Ves | — | 75 | — | Disa | 2007 |
| Baker & Myers | Years From Here | — | 75 | — | Mcg/curb Records | 1996 |
| Vertical Worship | Yes I Will | — | 75 | Other | — | 2019 |
| Nicki Minaj | Yikes | PO Quick Edit - Clean | 75 | Hip-Hop | PO Quick Edit - Clean | 2020 |
| Nicki Minaj | Yikes | PO Intro Edit - Clean | 75 | Hip-Hop | PO Intro Edit - Clean | 2020 |
| Nicki Minaj | Yikes | Clean Edit | 75 | Hip-Hop | Clean Edit | 2020 |
| Nicki Minaj | Yikes | Explicit | 75 | Hip-Hop | Explicit | 2020 |
| Big Circo | Yo No Fui | — | 75 | — | Emi Latin | 2002 |
| Domingo Quinones | Yo Te Conozco | — | 75 | — | Rmm Records | 2001 |
| Gifted Finalists | You Are My King (Amazing Love) | — | 75 | — | Forefront/Sparrow/EMI CMG | 2007 |
|
| David Archuleta | You Can | — | 75 | Pop | Jive/zomba | 2008 |
| Brantley Gilbert | You Don't Know Her Like I Do | — | 75 | Country | Valory | 2016 |
| Brantley Gibert | You Don't Know Her Like I Do | — | 75 | — | Big Machine | 2012 |
| Mac McAnally | You First | — | 75 | Ballad | Show Dog | 2009 |
| Whitney Houston | You Give Good Love | — | 75 | — | Arista | 2010 |
| Al Green & Lamorris Williams | You Make Me Happy | — | 75 | Top 40 | Rocks Landon | 2012 |
| Rico Richie ft. Snootie Wild | You Petty | Explicit | 75 | Hip-Hop | La Familia | 2016 |
| Billie Eilish | You Should See Me In A Crown | Vertical Video | 75 | Rock | Vertical Video | 2018 |
| Billie Eilish | You Should See Me In A Crown | — | 75 | Alternative | — | 2018 |
| Billie Eilish | You Should See Me In A Crown | Takashi Murakami Version | 75 | Rock | Takashi Murakami Version | 2019 |
|
| Jekalyn Carr | You Spoke Over Me | — | 75 | Other | Lunjeal | 2017 |
| Mariah Carey | You're Mine (Eternal) | — | 75 | Urban | Island/Island Def Jam | 2014 |
| Mariah Carey ft. Trey Songz | You're Mine (Eternal) | Remix | 75 | Top 40 | Island/Island Def Jam | 2014 |
| Greta Van Fleet | You're The One | — | 75 | — | — | 2019 |
| Carter's Chord | Young Love | — | 75 | Ballad | Show Dog | 2008 |