| Trouble 22 | World Shut Your Mouth | Urbania Remix | 125 | — | Red Rhythm | 2007 |
| Troyse | Body Count | — | 125 | Urban | Troyse | 2016 |
| Trylok | Radioactivity | — | 125 | — | — | — |
| Tujamo | Make U Love Me | Extended | 125 | Electronica | Spinnin | 2017 |
| Tujamo | Make U Love Me | — | 125 | Electronica | Spinnin | 2017 |
| Tujamo & Plastik Funk | Who | Original Mix | 125 | — | 3Beat | 2014 |
| Tweet | Cab Ride | Nicky P/FTL Mix | 125 | — | Atlantic | 2005 |
| Twiins | Boys, Boys, Boys | Darwich N-Joy Radio Mix | 125 | Dance | B | 2010 |
| Two Lanes ft. HYM | Long Way Home | Elenne Remix - Extended | 125 | House | Elenne Remix - Extended | 2018 |
| Ty Williams | Barn On The Rooftop | — | 125 | Country | Black River/Cherry Heart | 2009 |
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| Tyson | Die On The Dancefloor | Round Table Knights Remix | 125 | — | Back Yard | 2012 |
| U2 | Love Is Bigger Than Anything In Its Way | David Alvarado Remix | 125 | Progressive House | David Alvarado Remix | 2018 |
| U2 | Luckiest Man In The World | — | 125 | Rock | — | 2024 |
| U2 | Miracle Drug | — | 125 | — | — | — |
| Ultra DJs ft. TQ | What About U? | Ben Macklin Electro Dub | 125 | — | Nicetunes UK | 2007 |
| Ultra Nate | Free | — | 125 | — | Strictly Rhythm Records | 2005 |
| Ultra Nate | Love's The Only Drug | Funky Junction & Antony Reale Subliminal Strings Radio Edit | 125 | — | Tommy Boy Silver | 2006 |
| Ultra Nate & Michelle Williams | Waiting On You | * Digital Dog Intro Edit* | 125 | — | BluFire/Peace Bisquit | 2012 |
| Ultra Nate & Michelle Williams | Waiting On You | — | 125 | Dance | BluFire/Peace Bisquit | 2012 |
| Ultraviolet Sound | Suck My Kiss | Johnny Vicious Radio Edit | 125 | Dance | Odds On | 2010 |
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| Ultraviolet Sound | Suck My Kiss | — | 125 | Top 40 | Odds On | 2010 |
| Ultraviolet Sound | Suck My Kiss | Vicious Suck This Vocal Extended | 125 | — | Odds On | 2010 |
| Underset | Halogen | Orignal Mix | 125 | — | Street King | 2012 |
| Up Yours ft. Feral Is Kinky | London | Delgado Remix | 125 | — | Get Up | 2013 |
| Usher | More | RedOne Jimmy Joker Intro Edit | 125 | Top 40 | LaFace/Jive/Zomba | 2010 |