| Spada & Elen Levon | Cool Enough | Quick Edit* | 125 | Dance | Robbins | 2015 |
| Spada & Elen Levon | Cool Enough | Quick Edit | 126 | Dance | Robbins | 2015 |
| Spada & Elen Levon | Cool Enough | Mr. Belt & Wezol Remix | 124 | Dance | Robbins | 2015 |
| Spaha Social Feat. Mical Stone | Body & Soul | Main Mix | 123 | — | Unsigned | 2003 |
| Spankers ft. Barbara Clara | Tomamos En La Playa (Sex On The Beach) | — | 128 | — | Ultra | 2010 |
| Speaka Freaka | Clubland Essentials | That Mix | 127 | — | Unsigned | 2005 |
| Spencer Tarring ft. Angelika Vee | Fall Down | — | 128 | Dance | Revealed/Cloud 9 | 2015 |
| Spencer, Hill, Nadia Ali | Believe It | Cazzette's Androids Sound Hot Radio Edit | 128 | Dance | Strictly Rhythm | 2012 |
| Spencer, Hill, Nadia Ali | Believe It | — | 128 | Dance | Strictly Rhythm | 2012 |
| Spencer, Hill, Nadia Ali | Believe It | Cazzette's Androids Sound Hot Remix | 128 | — | Strictly Rhythm | 2012 |
|
| Spencer, Hill, Nadia Ali | Believe It | Club Mix | 128 | — | Strictly Rhythm | 2012 |
| Spencer, Hill, Nadia Ali | Believe It | Quick Edit | 128 | Dance | Strictly Rhythm | 2012 |
| Spencer, Hill, Nadia Ali | Believe It | Quick Edit* | 128 | Dance | Strictly Rhythm | 2012 |
| Spencer, Hill, Nadia Ali | Believe It | Ziggy Remix | 128 | — | Strictly Rhythm | 2012 |
| Spragga Benz | Cute & Little & Tight | Lp Version | 96 | — | Vp Records | 1999 |
| Spragga Benz | Money Yu Want | — | 94 | Dancehall | Jah Snowcone | 2011 |
| Spragga Benz | She Nuh Ready Yet | Lp Clean | 92 | — | Vp Records | 1998 |
| Spragga Benz ft. Katrina Willis | For You | Remix | 91 | — | Mirage Red Square Records | 2004 |
| Spragga Benz ft. Shabba Ranks, Kardinal Offishall & Swizz Beatz | Red Dot Special (Rha-Ta-Ta) | Clean Version | 87 | — | Boom Tunes | 2010 |
| Squa Lee ft. Sydney Ranee & MarciSax | Freedom | Extended | 124 | House | Extended | 2018 |
|
| Srta Dayana & Chacal | Apagame La Luz | — | 92 | Reggaeton | — | 2019 |
| Srta. Dayana & Chacal | Apagame La Luz | — | 92 | Reggaeton | — | 2019 |
| St. Louis Family Church ft. Chelsea Perry | My Whole World | — | 130 | Christian | Above | 2008 |
| Stafford Brothers & Eva Simons | This Girl | Radio Edit - No Rap | 128 | Dance | BMG Chrysalis | 2014 |
| Stagga Lee | Roll Wit M.v.p. | — | 86 | Hip-Hop | Artistdirect Records | 2003 |