| Scarlett Santana ft. C&C Music Factory | Rain | — | 78 | Top 40 | C&C Music Factory | 2011 |
| Scarlett Santana ft. C&C Music Factory | Rain | Dubstep Radio Edit | 71 | Dance | C&C Music Factory | 2011 |
| Scarlett Santana ft. C&C Music Factory | Rain | C&C Music Factory Best Friend Anthem Radio Edit | 128 | — | C&C Music Factory | 2011 |
| Schiller ft. Nadia Ali | Try | — | 123 | Dance | Radikal | 2012 |
| Scott Hardkiss ft. Lisa Shaw | Come On, Come On | Joe Claussell Dance Dance Version | 122 | — | God Within | 2011 |
| Scotty Boy & Luca Debonaire | Do You Realize | Original | 122 | House | Original | 2019 |
| Scotty Boy & Luca Debonaire | Takin' Over | Original | 124 | House | Original | 2019 |
| Sea Wolf | Old Friend | — | 74 | — | Dangerbird | 2014 |
| Seamus Haji vs JunkDNA & Olic | Aurora Lights | Seamus Haji Mix | 128 | — | Big Love | 2013 |
| Seamus Haji vs JunkDNA & Olic ft. The Frontrunnaz | After Midnight (Aurora Lights) | Sheldon Mix | 128 | — | Big Love | 2013 |
|
| Sean Ensign ft. Tamara Wallace | Feel The Music | 7th Heaven Club Mix | 131 | — | Titan Sounds | 2013 |
| Sean Ensign ft. Tamara Wallace & Slice | Feel The Music | 7th Heaven Remix | 131 | Dance | Titan Sounds | 2013 |
| Sean Ensign ft. Tamara Wallace & Slice | Feel The Music | — | 130 | Dance | Titan Sounds | 2013 |
| Sean Ensign ft. Tamara Wallace & Slice | Feel The Music | Johnny Labs Quick Edit | 131 | Dance | Titan Sounds | 2013 |
| Sean Ensign ft. Tamara Wallace & Slice | Feel The Music | Johnny Labs Radio Edit | 131 | Dance | Titan Sounds | 2013 |
| Sean Ensign ft. Tamara Wallace & Slice | Feel The Music | Johnny Labs Intro Edit | 131 | Dance | Titan Sounds | 2013 |
| Sean Garrett ft. Tgya & Gucci Mane | She Geeked | Clean Edit | 72 | Urban | Bet I Penned It/Interscope | 2010 |
| Sean Garrett ft. Tyga & Gucci Mane | She Geeked | — | 72 | — | Bet I Penned It/Interscope | 2010 |
| Sean Garrett ft. Tyga & Gucci Mane | She Geeked | Clean Edit | 72 | — | Bet I Penned It/Interscope | 2010 |
| Sean Garrett ft. Tyga & Gucci Mane | She Geeked | Instrumental | 72 | — | Bet I Penned It/Interscope | 2010 |
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| Sean Paul & David Guetta ft. Becky G | Mad Love | — | 98 | Pop | — | 2018 |
| Sean Paul & David Guetta ft. Becky G | Mad Love | Clean Edit | 98 | — | Clean Edit | 2018 |
| Sean Paul + David Guetta ft. Becky G | Mad Love | Clean Edit | 98 | Pop | Clean Edit | 2018 |
| Sean Paul + David Guetta ft. Becky G | Mad Love | Lyric Video | 98 | Top 40 | Lyric Video | 2018 |
| Sean Paul + David Guetta ft. Becky G | Mad Love | PopRoXxX Intro Edit | 98 | — | PopRoXxX Intro Edit | 2018 |