| Seven Lions ft. Tove Lo | Strangers | Extended Mix | 130 | — | Casablanca | 2014 |
| Sex-O-Sonique | I Thought It Was You | 12 Inch Mix | 127 | — | Ffrr Records | 1998 |
| Sextronica ft. Claudia Monet | Little Voices | Lyric Video - Explicit | 128 | Dance | Lyric Video - Explicit | 2019 |
| Sextronica ft. Claudia Monet | Little Voices | StoneBridge Extended House Mix | 126 | House | StoneBridge Extended House Mix | 2019 |
| Sha Sha Jones ft. Super Jay | Lose You | — | 58 | — | Music Minds | 2011 |
| Shachah ft. John Wells - The Tonic | Deliver Us | — | 92 | Christian | Cross Movement | 2009 |
| Shae Jones Feat. Cha Cha | Talk Show Shhh! | — | 85 | — | Universal Records | 1999 |
| Shaggy & Rayvon | Shaggy & Rayvon Show | — | 87 | Dancehall | Bigyard Music | 2007 |
| Shaggy & Wayne Wonder | Make Up | — | 89 | Dancehall | Ranch | 2012 |
| Shaggy Feat. Brian & Tony Gold | Hey Sexy Lady | — | 102 | — | Big Yard/mca Records | 2002 |
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| Shaggy Feat. Brian & Tony Gold | Leave It To Me | — | 77 | — | Mca Records | 2001 |
| Shaggy Feat. Janet Jackson | Luv Me, Luv Me | Lp Clean | 97 | — | Flyte Tyme/mca Records | 1998 |
| Shaggy Feat. Rayvon | Angel | — | 85 | — | Mca Records | 2001 |
| Shaggy ft. Akon | What's Love | — | 105 | Dancehall | Big Yard/VP | 2008 |
| Shaggy ft. Barrington Levy | Broadway | Buda Mix | 90 | — | Big Yard Geffen | 2006 |
| Shaggy ft. Janet Jackson | Luv Me, Luv Me | — | 97 | Reggae | Flyte Tyme/MCA | 2013 |
| Shaggy ft. Rayvon | Angel | — | 85 | — | MCA | 2005 |
| Shaggy ft. Rik Rok & Tony Gold | Bonafide Girl | — | 98 | Urban | VP | 2007 |
| Shaggy ft. Rik Rok & Tony Gold | Bonafide Love | — | 98 | Dancehall | Big Yard | 2007 |
| Shaggy ft. Tony 'CD' Kelly | Our Future | — | 100 | Dancehall | — | 2018 |
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| Shaggy ft. Wayne Wonder | Make Up | Quick Edit | 89 | Urban | Ranch | 2012 |
| Shaggy ft. Wayne Wonder | Make Up | — | 89 | Urban | Ranch | 2012 |
| Shake Black & Tony Haze | Dame Un Beso | — | 92 | Reggaeton | Warner Latina | 2006 |
| Shake Black & Tony Haze | La Tripleta | — | 93 | Reggaeton | Warner Latina | 2006 |
| Shalone | Step Up | — | 70 | Urban | Foul Mouf | 2016 |