| Sagaz Musical | Corazon Duro | — | 70 | — | Univision | 2007 |
| Sagaz Musical | Tengo Miedo | — | 139 | — | Univision Records | 2007 |
| Sagaz Musical | Tomar, Sufrir Y Llorar | — | 63 | — | Univision | 2006 |
| Saigon ft. Just Blaze | Gotta Believe It | Explicit | 83 | — | Amalgam Digital/E1 | 2009 |
| Salazar Pakyo | Ground X | — | 128 | Dance | Tazmania | 2015 |
| Salazar Pakyo & Visioc ft. Andre Linman | Summer Of Our Lives | Quick Edit | 128 | Dance | Tazmania | 2015 |
| Salazar Pakyo & Visioc ft. Andre Linman | Summer Of Our Lives | — | 128 | Dance | Tazmania | 2015 |
| Salazar Pakyo & Visioc ft. Andre Linman | Summer Of Our Lives | Radio Edit | 128 | Dance | Tazmania | 2015 |
| Sancocho Feat. Amazona | Se Parece A Ti | — | 151 | — | Cutting Records | 1999 |
| Sancocho ft. Amazona | Se Parece A Ti | — | 151 | — | Cutting | 2007 |
|
| Sasha Lazard | Awakening | Minge Binge Vocal | 128 | — | High Octaine Records | 2002 |
| Sasha Lazard | Battle Of Erishkigal | Minge Binge Vocal Mix | 130 | — | Omtown/higher Octave Music | 2003 |
| Sasha Lazard | Battle Of Erishkigal | Wes Wallace Full Vocal | 125 | — | Omtown/higher Octave Music | 2003 |
| Sati Kazanova | Happiness Hey | — | 125 | Top 40 | Ragoza | 2017 |
| Saweetie & London On Da Track ft. G-Eazy & Rich The Kid | Up Now | Explicit | 104 | Urban | Explicit | 2018 |
| Scotty Marz vs. Rob Razor | All The Ho's | Original Mix | 129 | — | Scotty Marz (unsigned) | 1999 |
| Seamus Haji vs JunkDNA & Olic ft. The Frontrunnaz | After Midnight (Aurora Lights) | Sheldon Mix | 128 | — | Big Love | 2013 |
| Sean Paul + Major Lazer | Tip Pon It | — | 110 | — | — | 2018 |
| Sex Krazed Superstars | Da Horniest | — | 133 | — | Underground Construction Records | 1997 |
| Shab Maze | All I Ever Wanted | — | 110 | Urban | Shab Pack | 2016 |
|
| Shabazz Palaces | Are You...Can You...Were You? (Felt) | (Explicit) | 73 | — | Sub Pop | 2012 |
| Shabazz Palaces & Tendai | Blastit... | — | 82 | Urban | Templar | 2011 |
| Shabazz Palaces & Tendai | Blastit... | (Explicit) | 82 | — | Templar | 2011 |
| Shake Black & Tony Haze | Dame Un Beso | — | 92 | Reggaeton | Warner Latina | 2006 |
| Shake Black & Tony Haze | La Tripleta | — | 93 | Reggaeton | Warner Latina | 2006 |